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Meet the Investigators

LLF’s investigators are some of the most innovative and creative thinkers working today in medical science. The research we have funded over the years has enabled several groundbreaking discoveries that have made a difference in health and longevity.

Blood Cancer

Red Blood Cells
Grant Challen

Grant Challen, Ph.D

Predicting – and Preventing – Blood Cancer? An Essential Conversation.

A recent recipient of funding from The Longer Life Foundation, Dr. Grant Challen, Associate Professor Department of Medicine, Oncology Division and Stem Cell Biology at Washington University School of Medicine in St. Louis, leads a lab studying ways to identify genes that can be targeted to diagnose blood …

Metabolism, Nutrition, and Aging

Metabolism-Nutrition-Aging
Bettina Mittendorfer

Bettina Mittendorfer, Ph.D.

Metabolism, Nutrition, and Longevity: Finding the Keys

In 2019, Bettina Mittendorfer, Ph.D., Professor of Medicine, Division of Geriatrics and Nutritional Science, Washington University School of Medicine in St. Louis, was named Director of the Longer Life Foundation’s Longevity Research Program (LRP). Here, she discusses how her strong interest in human longevity will inform …

Biochemistry of Protein Misfolding

Biochemistry of Protein Misfolding
Meredith Jackrelpng

Meredith Jackrel, Ph.D.,

Disaggregases and Protein Misfolding: A Q&A

Meredith Jackrel, Ph.D., an Assistant Professor of Chemistry at Washington University in St. Louis, researches biochemistry of protein misfolding with a focus on the role of disaggregases. The Longer Life Foundation is a proud supporter of Dr. Jackrel’s research into restoring proteostasis to counter human disease.

Convalescent Plasma (CP)

Convalescent Plasma
Jeffery Henderson
Jeffrey P. Henderson, M.D., Ph.D.
Convalescent Plasma and COVID-19
Jeffrey P. Henderson, M.D., Ph.D., a Longer Life Foundation alumni grant recipient and a researcher with Washington University School of Medicine, is one of the scientists at the forefront of research into convalescent plasma (CP) from those who have recovered from COVID-19 to help those with active disease.

Human Aging

Human Aging Diet
Luigi Fontana
Luigi Fontana, M.D., Ph.D.
Calorie Restriction and the Future of Aging

Luigi Fontana, M.D., Ph.D., FRACP, is an internationally known human systems biologist and a world leader in the study of nutrition and the biology of human aging. A former LLF grant recipient, his focus is on calorie restriction and its potential role in human longevity. 

Polycythemia Vera

Polycythemia Vera
Steven Oh
Stephen T. Oh, M.D., Ph.D.
Polycythemia Vera: A Researcher’s View

Stephen T. Oh, M.D., Ph.D., heads a research group at Washington University School of Medicine in St. Louis that is focused on the pathogenesis of myelo- proliferative neoplasm (MPN) with the goal of translating the work into improved therapies for MPN patients.