Research
Grants by the Longer Life Foundation have supported hundreds of academicians and scientists engaged in fundamental research into longevity and health. LLF-supported research investigations produce groundbreaking results as well as substantial subsequent support by major research institutions.
Since LLF’s founding in 1998:
investigations have been funded.
peer-reviewed research articles have been published, citing LLF support.
Our Mission: The Longer Life Foundation’s mission is to fund and support the study of factors that either predict the mortality and morbidity of select populations or influence improvements in longevity, health, and wellness.
View All Longer Life Foundation Grants
Grants 2025
AWARDED: 2025
Reprogramming AAA Proteases for Personalized Cancer Immunotherapy
Alireza Ghanbarpour, Ph.D.
Investigation Year: 1
AWARDED: 2025
A Novel Neurophysiological Biomarker for MS Disease Progression
Laura McPherson, DPT, Ph.D.
Investigation Year: 1
AWARDED: 2025
AI-Driven Mortality Prediction: Integrating Biological, Psychosocial, and Linguistic Predictors of Mortality Using Deep Learning Transformer Models
Joshua R. Oltmanns, Ph.D.
Investigation Year: 1
AWARDED: 2025
Impact of the Ketogenic Diet on Cholesterol Synthesis and Cholesterol Absorption
Max Petersen, M.D., Ph.D.
Investigation Year: 1
AWARDED: 2025
Enhancing Muscle Mass and Metabolism to Combat Muscle Dysfunction
Rita T. Brookheart, Ph.D.
Investigation Year: 2 of 2
AWARDED: 2025
Investigating Protein Prenylation in Aging
Monika Bambouskova, Ph.D.
Investigation Year: 1
AWARDED: 2025
Investigating Geographic Disparities in Social
Determinants of Health and Hypertension in the
Greater St. Louis Area
Lindsay Underhill, M.P.H., Ph.D.
Investigation Year: 2 of 2
AWARDED: 2025
High-content Approach to Predict Cancer Predisposing Germline Mutations in BRCA1 Gene
Priyanka Verma, B.S., M.S., Ph.D.
Investigation Year: 2 of 2
AWARDED: 2025
Evaluation of Neuronal Changes Associated with Healthy Aging and Alzheimer’s Disease in Directly Converted Human Neurons
Eva Klinman, M.D., Ph.D.
Investigation Year: 2 of 2
Grants 2024
AWARDED: 2024
Mitigating Doxorubicin Toxicity Utilizing Dietary Interventions to Reduce Skeletal Muscle Loss and Prevent Cardiomyopath
Ali Javaheri, M.D., Ph.D. (Longevity Research Program)
Investigation Year: Longevity
AWARDED: 2024
Exfoliome Characterization of Alzheimer’s Disease Patients
Gautam Dantas, Ph.D.
Investigation Year: 2 of 2
AWARDED: 2024
Neuronal Activity-Dependent DNA Repair in Healthy Aging
Elizabeth Pollina, Ph.D.
Investigation Year: 2 of 2
AWARDED: 2024
Investigating Geographic Disparities in Social
Determinants of Health and Hypertension in the
Greater St. Louis Area
Lindsay Underhill, M.P.H., Ph.D.
Investigation Year: 1
AWARDED: 2024
Enhancing Muscle Mass and Metabolism to Combat Muscle Dysfunction
Rita Brookheart, Ph.D.
Investigation Year: 1
AWARDED: 2024
Anti-Senescent Approaches to Adipose Tissue in Aging
Kathleen Markan, Ph.D.
Investigation Year: 1
AWARDED: 2024
High-content Approach to Predict Cancer Predisposing Germline Mutations in BRCA1 Gene
Priyanka Verma, B.S., M.S., Ph.D.
Investigation Year: 1
AWARDED: 2024
Evaluation of Neuronal Changes Associated with Healthy Aging and Alzheimer’s Disease in Directly Converted Human Neurons
Eva Klinman, M.D., Ph.D.
Investigation Year: 1
Grants 2023
AWARDED: 2023
Glioblastoma and the Senescent Brain Microenvironment
Milan G. Chheda, M.D.
Investigation Year: 2 of 2
AWARDED: 2023
Exfoliome Characterization of Alzheimer’s Disease Patients
Gautam Dantas, Ph.D.
Investigation Year: 1
AWARDED: 2023
Peroxisomal Fatty Acid Metabolism and Kidney Aging
Leslie Gewin, M.D.
Investigation Year: 1
AWARDED: 2023
Amplification Loop Between Mitochondria and Complement in ARDS
Hrishikesh S. Kulkarni, M.D.
Investigation Year: 2 of 2
AWARDED: 2023
Pathogenesis and Outcomes of Invasive S. Aureus Infections
Laura Marks M.D., Ph.D.
Investigation Year: 2 of 2
AWARDED: 2023
Targeting Excessive Mitophagy to Mitigate Age-Related Muscle Dysfunction
Natalie M. Niemi, Ph.D.
Investigation Year: 1
AWARDED: 2023
Neuronal Activity-Dependent DNA Repair in Healthy Aging
Elizabeth Pollina, Ph.D.
Investigation Year: 1
AWARDED: 2023
Long Non-Coding RNAs as Biomarkers for Multiple Myeloma Progression
Jessica Silva-Fisher, Ph.D.
Investigation Year: 1
AWARDED: 2023
Longer Life Foundation Longevity Research Program (LRP)
Ali Javaheri, M.D., Ph.D.
Investigation Year: 2 of 3
Grants 2022
AWARDED: 2022
Factors Involved in Diabetes and Atherosclerosis
Longevity Research Program, Bettina Mittendorfer, Ph.D.
Investigation Year: 1 of 3
AWARDED: 2022
The Role of Complement in Hypertensive Disorders of Pregnancy
Anuja Java, M.D., Ph.D.
Investigation Year: 2 of 2
AWARDED: 2022
Glioblastoma and the Aging Brain
Milan G. Chheda, M.D.
Investigation Year: 1
AWARDED: 2022
Defining the Role of Neuroinflammation in Vascular Cognitive Impairment
Peter Kang, M.D., MSCI
Investigation Year: 1
AWARDED: 2022
Pathogenesis and Molecular Epidemiology of S. Aureus Isolates Associated With Invasive Infections Among PWID
Laura Marks, M.D., Ph.D.
Investigation Year: 1
AWARDED: 2022
Long Non-coding RNAs as Biomarkers for Multiple Myeloma Progression
Jessica Silva-Fisher, Ph.D.
Investigation Year: 1
Grants 2021
AWARDED: 2021
Dietary protein and cardiovascular health
Longevity Research Program, Bettina Mittendorfer, Ph.D.
Investigation Year: 3 of 3
AWARDED: 2021
Alex Holehouse, M.Sc. Ph.D.
Investigation Year: 2 of 2
AWARDED: 2021
Defining the Role of Intestinal Immune Cell Balance and its Association With Obesity
Devesha Kulkarni, M.Sc., Ph.D.
Investigation Year: 1
AWARDED: 2021
Angiogenic Imbalance and Diastolic Dysfunction in Preeclampsia
Kathryn Lindley, M.D.
Investigation Year: 2 of 2
AWARDED: 2021
The Role of Complement in Hypertensive Disorders of Pregnancy
Anuja Java, M.D.
Investigation Year: 1
AWARDED: 2021
Targeting the Amplification Loop Between Mitochondria and Complement Activation in Acute Respiratory Distress Syndrome (ARDS)
Hrishikesh Kulkarni, M.D., MSCI
Investigation Year: 1
AWARDED: 2021
Targeting Receptor Interactions With SVEP1, a Circulating Biomarker of Longevity in Humans
Nathan Stitziel, M.D. Ph.D.
Investigation Year: 1
AWARDED: 2021
Determining Causes and Potential Preventability of Clinical Deterioration Among Oncology Inpatients
Patrick Lyons, M.D.
Investigation Year: 1
Grants 2020
AWARDED: 2020
Prognostic Biomarkers of Severe Disease in COVID-19 Patients
Jeffrey Henderson, M.D., Ph.D.
Investigation Year: 1
AWARDED: 2020
Clinic to Community Connections
Cynthia Herrick, M.D. MPHS
Investigation Year: 1
AWARDED: 2020
Predicting the Functional Impact of Genetic Variation Within Intrinsically Disordered Protein Regions
Alex Holehouse, M.Sc., Ph.D.
Investigation Year: 1 of 2
AWARDED: 2020
Defining the Role of Intestinal Immune Cell Balance and its Association With Obesity
Devesha Kulkarni, M.Sc., Ph.D.
Investigation Year: 1
AWARDED: 2020
Angiogenic Imbalance and Diastolic Dysfunction in Preeclampsia
Kathryn Lindley, M.D.
Investigation Year: 1 of 2
AWARDED: 2020
Dietary Protein and Cardiovascular Health
Longevity Research Program, Bettina Mittendorfer, Ph.D.
Investigation Year: 2 of 3
AWARDED: 2020
DNA Methylation in Alzheimer’s Disease
Carolina Soriano-Tarraga, M.Sc. Ph.D.
Investigation Year: 1