Research - 2000s
Grants by the Longer Life Foundation have supported hundreds of academicians and scientists engaged in fundamental research into longevity and health. LLF-supported research investigations produce groundbreaking results as well as substantial subsequent support by major research institutions.
Since LLF’s founding in 1998:
investigations have been funded.
peer-reviewed research articles have been published, citing LLF support.
Our Mission: The Longer Life Foundation’s mission is to fund and support the study of factors that either predict the mortality and morbidity of select populations or influence improvements in longevity, health, and wellness.
View All Longer Life Foundation Grants
Grants 2009
AWARDED: 2009
Does a Low Protein Diet Slow Aging, Protect Against Cancer and Inhibit Prostate Cancer Growth?
Investigation Year: 1 of 2
AWARDED: 2009
Does Caloric Restriction Slow Aging of the Human Immune System?
Marco Colonna, M.D.
Investigation Year: 1 of 2
AWARDED: 2009
Diagnostic and Therapeutic Applications of a Novel Plasma Metabolite, Nicotinamide Mononucleotide (NMN), for Age-Associated Metabolic Complications in Humans
Shin-ichiro Imai M.D., Ph.D.
Investigation Year: 2 of 2
AWARDED: 2009
Novel Proteins as Urinary Biomarkers of Renal Cell Carcinoma
Jeremiah Morrissey Ph.D.
Evan Kharasch M.D., Ph.D.
Investigation Year: 1
AWARDED: 2009
Novel Methods for Detection of Coronary Artery Disease in Diabetic Patients
Ravi Rasalingam, M.D.
Investigation Year: 2 of 2
AWARDED: 2009
MicroRNA Expression Signatures to Predict Cervical Cancer Outcome
Xiaowei Wang, Ph.D.
Investigation Year: 1
Grants 2008
AWARDED: 2008
Longevity Research Program
Director: John O Holloszy, M.D.
Associate Director: Luigi Fontana, M.D., Ph.D.
Investigation Year: 1
AWARDED: 2008
Fitness-to-Drive in Older Adults with Stroke
David B. Carr, M.D.
Investigation Year: 2 of 2
AWARDED: 2008
Diagnostic and therapeutic applications of a novel plasma metabolite, nicotinamide mononucleotide (NMN), for age-associated metabolic complications in humans
Shin-ichiro Imai, M.D., Ph.D.
Investigation Year: 1 of 2
AWARDED: 2008
Modulation of Aging and Calorie Restriction Benefits by PGC-1α
John J. Lehman, M.D.
Investigation Year: 1
AWARDED: 2008
Omega-3 Fatty Acids for the Treatment of the Anabolic Resistance of Skeletal Muscle in Older Adults
Bettina Mittendorfer, Ph.D.
Investigation Year: 1
AWARDED: 2008
Identification of Significant Coronary Artery Disease at Rest With Integrated Backscatter Imaging and Myocardial Strain
Ravi Rasalingan, M.D.
Investigation Year: 1 of 2
Grants 2007
AWARDED: 2007
Fitness-to-Drive in Neurologically Impaired Older Adults
David B. Carr, M.D.
Investigation Year: 1 of 2
AWARDED: 2007
Effects of Calorie Restriction on Markers of Aging and Longevity
Luigi Fontana, M.D., Ph.D.
Investigation Year: 2 of 2
AWARDED: 2007
Undercarboxylated Matrix Gla Protein (ucMGP): A Novel Biomarker to Predict Coronary Artery Calcification
Investigation Year: 1
AWARDED: 2007
Dependence of Longevity and Health on TRB3 Genotype
Investigation Year: 2 of 2
AWARDED: 2007
Comprehensive Assessment of Senior Adult Cancer Patients
Jay Piccirillo, M.D.
Investigation Year: 1
Grants 2006
AWARDED: 2006
Effects of Calorie Restriction on Mmarkers of Aging and Longevity
Luigi Fontana, M.D., Ph.D.
Investigation Year: 1 of 2
AWARDED: 2006
Minimally Invasive Staging of the Axilla in Breast Cancer
Investigation Year: 1
AWARDED: 2006
Dependence of Longevity and Health on TRB3 Genotype
Anthony J. Muslin, M.D.
Investigation Year: 1 of 2
AWARDED: 2006
International Collaborative Study of Social Support
Investigation Year: 2 of 2
Grants 2005
AWARDED: 2005
Mental Health History and Survival among Breast Cancer Patients
Mark S. Walker, Ph.D.
Investigation Year: 1
AWARDED: 2005
Regulation of Longevity by Anticonvulsant Medicines
Investigation Year: 1
AWARDED: 2005
Activity Portfolios: Engagement and Health in Later Life
Investigation Year: 1
AWARDED: 2005
The Effect of the C488&A Polymorphism of the CYP1A1 Gene on Cognitive Function
Investigation Year: 1
Mini-Grants 2005
AWARDED: 2005
Collection of Preliminary Data on the Interaction of Social Engagement and Stress in Older Adults
Dorothy Edwards, Ph.D.
Investigation Year: 1
AWARDED: 2005
Environmental Features that Influence Social Engagement of Older Adults Residing in Congregate Living Facilities
Susan Stark, Ph.D.
Investigation Year: 1
AWARDED: 2005
Denise Wilfley, Ph.D.
Investigation Year: 1
Grants 2004
AWARDED: 2004
Food For Thought: An Internet-based Treatment Program for Childhood Obesity
Investigation Year: 1
AWARDED: 2004
Ginseng in Prevention and Treatment of Diabetes
Investigation Year: 1
AWARDED: 2004
Development of Multidisciplinary Approach to Obesity
Investigation Year: 1
AWARDED: 2004
Projecting Individualized Cancer-Specific Death Risks and Other Competing Cause Death Risks Among Elderly Men Diagnosed With Prostate Cancer
Jay Piccirillo, M.D. F.A.C.S.
Investigation Year: 1
Mini-Grants 2004
AWARDED: 2004
Inflammatory Cytokines and Physical Frailty in Obese Elderly Subjects
Dennis T Villareal, M.D.
Investigation Year: 1
AWARDED: 2004
Early Intervention of Eating- and Weight-Related Problems Via the Internet in Overweight Adolescents: A Randomized Controlled Trial
Denise Wilfley, Ph.D.
Investigation Year: 1
Grants 2003
AWARDED: 2003
International Cooperative Study of Social Support
Edwin Fisher, Ph.D.
Investigation Year: 1 of 2
AWARDED: 2003
The Key Features Inventory: Early Diagnosis of Dementia to Improve Quality of Life
Investigation Year: 1
AWARDED: 2003
Pharmacologic Compounds That Extend C. elegans Life Span
Investigation Year: 1
Mini-Grants 2003
AWARDED: 2003
Influence of Exercise and Dietary Patterns on Weight Gain Throughout College
Susan S Deusinger, Ph.D.
Susan Racette, Ph.D.
Investigation Year: 1
AWARDED: 2003
Predictors of Survival in Patients with Primary Pulmonary Hypertension Wait-listed for Lung Transplantation
Investigation Year: 1
Mini-Grants 2002
AWARDED: 2002
Long-Term Adjustment and Quality of Life Among Breast Cancer Survivors Following Treatment
Teresa Deshields, Ph.D.
Laura Bayer, Ph.D.
Investigation Year: 1
AWARDED: 2002
Physician-Related Barriers to Colorectal Cancer Screening in Missouri
Dayna S. Early, M.D.
Steve Ristvedt, Ph.D.
Mario Schootman, Ph.D.
Investigation Year: 1
AWARDED: 2002
Markers of Cognitive Change in an Aging Population: Early Diagnosis of Dementia to Improve Quality of Life
James E. Galvin, M.D.
Investigation Year: 1
AWARDED: 2002
Psychosocial Factors Associated with Delay in Diagnosis among Locally Advanced Breast Cancer Patients
Donna Jeffe, Ph.D.
Investigation Year: 1
AWARDED: 2002
Abdominal Pain Evaluation Tool (APET) Pilot Project
Larry Lewis, M.D.,
Investigation Year: 1
Grants 2001
AWARDED: 2001
Risk Adjustment in the Medicare Atrial Fibrillation Population
Brian F. Gage, M.D. M.Sc.
Investigation Year: 1
AWARDED: 2001
Data Mining Approaches to Suicide and Suicidal Behaviors
Rumi Kato Price, Ph.D. M.P.E.
Investigation Year: 1
AWARDED: 2001
Disease Comorbidity and Survival in the NHLBI Family Heart Study
Michael Province, Ph.D.
Investigation Year: 1
Grants 2000
AWARDED: 2000
Health-Related Quality of Life: A Strategy for Improving Physician-Patient Communication and Patient Outcomes
Thomas E. Burroughs, Ph.D.
Radhika Desikan, Ph.D.
Investigation Year: 1
AWARDED: 2000
Productive Engagement in Older Adults: Effects on Well Being and Mortality
Nancy Morrow-Howell, Ph.D.
Investigation Year: 1
AWARDED: 2000
Breast Cancer Screening and Disability
Mario Schootman, Ph.D.
Investigation Year: 1
AWARDED: 2000
Enhanced Diabetes Self-Management Using Peer Health Coaches
Investigation Year: 1